eCM Meeting Abstracts 2024, Collection 1
2024 ARI Orthopaedics Conference - Orthopaedic Infection
Meeting Abstracts
Oral presentations: click here to download all the abstracts in one file
Poster presentations: click here to download all the abstracts in one file
Oral presentations
Page 1: M Morgenstern
Fracture-related infection: perspectives of an orthopaedic-trauma surgeon
Page 2: Y Achermann
Prevention and treatment of implant-associated infection: an ID physician perspective
Page 3: MC MacKechnie, JE Quintero, R Amadei, M Rio, R Madrigal, T Miclau
Clinical outcome predictors and rates of infection following open tibia fractures in Latin America
Page 4: D Raafat, A. Rakow, L Schröder, A Hofer, S Wiebe, J Schoon, S Weiss, BM Bröker, GI Wassilew, V Janz
Antibody response to periprosthetic joint infection – Insights from a pilot study
Page 5: D Bumann
Phenotyping bacteria in the in vivo environment
Page 6: N Hickok
The changing joint environment: bacterial responses
Page 7: E Seebach, CE Pérez-Cevallos, KF Kubatzky
cGAS-STING Pathway in Orthopaedic Infections
Page 8: B Pascoe, J Littlefair, SK Sheppard
Comparative genomics and the evolution of pathogenic staphylococci
Page 9: J Cassat
Bone appétit: bacterial pathogenesis during Staphylococcus aureus osteomyelitis
Page 10: U Neugebauer
Characterization of S. aureus-induced bone deformation using fluorescence and Raman imaging
Page 11: H Meghwani, KM Sandercock, KA McDonald, M Saito, R Constantine, S Lenigk, A Rodriguez, JR Owen, SL Kates, EM Schwarz, G Muthukrishnan
CCL20/CCR6 axis is essential to limiting the disease severity in Staphylococcus aureus osteomyelitis
Page 12: Y Ren, KL de Bentley, J Weeks, T Xue, Y Shu, AJ Hui Tay, S Lekkala, SCA Yeh, EM Schwarz, C Xie
Osseointegration of hydroxy bisphosphonate-conjugated sitafloxacin (HBCS) during skeletal growth and fracture healing in a mice model
Page 13: T Coenye
Novel approaches to study biofilm biology in the context of prosthetic joint infections
Page 14: JW Veening
Uncovering mechanisms of host-pathogen interactions using CRISPR interference
Page 15: JL Hamilton, TM Schmid, J Rhodes, A Markovics, SD Goodman, LO Bakaletz, MA Wimmer
Titanium coated with anti-DNABII monoclonal antibody disrupts bacterial biofilm
Page 16: B Chen, LP Benavente, M Chittò, V Post, C Constant, S Zeiter, P Nylund, M D’Este, MG Moreno, A Trampuz, J Wagemans, R Lavigne, J Onsea, RG Richards, WJ Metsemakers, TF Moriarty
Carboxymethyl cellulose hydrogel containing phage cocktail and vancomycin for topical delivery against fracture-related infections
Page 17: S Cometta, L Chai, DW Hutmacher
An in vitro model to study implant-associated biofilms using a GelMA-based 3D microenvironment
Page 18: H van der Mei
Bacterial outer membrane vesicles for targeted treatment of bacterial infections
Page 19: X Wang
Antimicrobial chiral polymers and carrier free nanodrugs
Page 20: G Mannala, M Rupp, N Walter, R Youf, S Bärtl, V Alt, M Riool
Repetitive combined doses of bacteriophages and gentamicin protect against Staphylococcus aureus implant-related infections in Galleria mellonella
Page 21: V Pennone, E Angelini, D Sarlah, AB Lovati
Synthesis and antibacterial activity of LL-37-derived antimicrobial peptides as potential treatment of orthopaedic infections
Page 22: B Wildemann
Bone fracture non-union
Page 23: H Simpson
How infection changes non-union treatment
Page 24: K Trenkwalder, S Erichsen, F Weisemann, P Augat, S Hackl
The diagnosis of low-grade infection in presumed aseptic femoral or tibial shaft nonunion by membrane filtration of sonication fluid
Page 25: P Fehrenbach, F Weisemann, C Siverino, K Trenkwalder, L Bürgi, S Hackl, SAJ Zaat, EC de Jong, TF Moriarty
Increased number of Th1 cells and monocytes is associated with infected non-union in patients with long bone fracture
Page 26: A Montali
Translation of infection-focused technologies to the clinic
Page 27: C Arts
Material technology to tackle Antimicrobial Resistance; the NWA DARTBAC project
Page 28: S Häckel
Spondylodiscitis and implant-related spinal Infections: Current challenges and needs from a surgeon's perspective
Page 29: S Rajasekaran
Can sub-clinical infection be the cause for disc degeneration and back pain? - Evidences from metagenomic, proteomic and metabolomic studies
Page 30: A Nüesch, E Kanelis, L Alexopoulos, F Williams, B Gantenbein, M Lacey, LC Le Maitre
Exploring Gram-positive bacteria within the intervertebral disc: what is their potential influence?
Page 31: C Feng, C Liu, J Long, Y Zhou, C Li, B Huang
Comparison of the diagnostic efficacy of blood and tissue metagenomes in primary spinal infection
Page 32: L Zhang
Micro- and nanorobots for biofilm eradication
Page 33: S Green
Making antibiotics great again: Phage resistance correlation with resensitivity to antibiotics in pan-resistant P. aeruginosa
Page 34: C Siverino, L Gens, M Ernst, T Bucholz, M Windolf, S Zeiter, RG Richards, M Morgenstern, TF Moriarty
Debridement, antibiotics, irrigation, and implant retention in a preclinical model of FRI in sheep
Page 35: Y Ren, KL de Bentley, J Weeks, T Xue, Y Shu, AJH Tay, S Lekkala, SA Yeh, EM Schwarz, C Xie
Real-time fluorescent microscopy assessment of PAD4-mediated NETosis and NET degradation by S. aureus nuclease during nidus formation on implants
Page 36: E Schwarz - Berton Rahn Award winner 2024
Elucidating the osteoimmunology of bone infection and development of a passive immunization for S. aureus osteomyelitis
Berton Rahn Research Award winner 2023 (booklet)
Poster presentations
Page P1: G Babuccu, M Riool, SAJ Zaat
Microbial interactions and treatment strategies in Staphylococcus aureus – Candida albicans dual-species biofilms
Page P2: L Bessems, B Chen, S Uyttebroek, J Onsea, WJ Metsemakers
Neutralising antibody response against locally applied bacteriophages in patients with musculoskeletal infections
Page P3: W Boot, V Post, TF Moriarty, P Wahl
Gentamicin fails to eradicate Staphylococcus aureus biofilm in vitro, even in combination with rifampin
Page P4: JD Brodell, Jr, A Rodenhouse, HJF Shaikh, JT Cushman, JT Gorczyca
Tracking the pre-hospital course of open fracture patients
Page P5: C Calligaro, A Akkache, L Lieu, L Petit, J Li, S Hathroubi, P Lavalle, NE Vrana
Portable spray device for applying an antimicrobial coating during surgery to surgical tools and implants
Page P6: B Chen, C Peez, M Chittò, V Post, D Arens, TF Moriarty
Evaluating the safety and pharmacokinetics of systemic versus local phage therapy in health sheep
Page P7: M Chittò, W Feng, X Wang, TF Moriarty
Targeted poly (D-amino acids) nanoparticles loaded with sitafloxacin for staphylococcal biofilm eradication
Page P8: S Cometta, BC Donose, A Juárez-Saldivar, A Ravichandran, Y Xu, N Bock, T Dargaville, AD Rakic, DW Hutmacher
Development and characterization of an antibacterial implant surface – proof of concept of albumin/tannic acid-coated 3D printed polycapro-lactone scaffolds
Page P9: GA Coppola, L Maetens, HP Steenackers, EV Van der Eycken
Biofilm triggered antimicrobial release coating for implantable devices based on pH-liable boron-diols interactions
Page P10: YN Fu, TF Moriarty, X Wang
Carrier-free nanodrugs for the treatment of multidrug-resistant infection
Page P11: JL Hamilton, S Gianotti, J Fischer, G Della Fara, A Impergre, F De Vecchi, MJ Abu Alia, A Fischer, A Markovics, MA Wimmer
Electrophoretic deposition of gentamicin into titanium nanotubes prevents prosthetic joint infection
Page P12: Y Jiang, L Wang
Disc penetration sign: a distinctive mri sign indicating the severity of pyogenic spondylitis
Page P13: EMA Kuhn, X Chen, M Chittò, X Wang, TF Moriarty
Combining sitafloxacin and sugars to targeting stationary phase Staphylococcus aureus
Page P14: S Le, L Wang
Floating disc: a distinctive mr imaging manifestation of native vertebral osteomyelitis
Page P15: R Li, L Asri, O De Luca, H Zhang, I Chen, BJ Kooi, B van de Belt-Gritter, AM Slomp, HJ Busscher, P Rudolf, HC van der Mei, TJA Loontjen
Towards biocompatible immobilized antibacterial coatings on titanium which kill bacteria on contact by electrostatic forces
Page P16: GK Mannala, B Labat, G Ladam, P Thébault, N Walter, D Szymski, M Riool, V Alt, M Rupp
Antibacterial properties of nisin layer-by-layer based coating on titanium k-wires in galleria mellonella implant-associated infection model
Page P17: C Siverino, P Nylund, AL Foster, W Boot, S Zeiter, RG Richards, A Montali, M D'Este, TF Moriarty
In vitro and in vivo evaluation of a gentamycin-vancomycin loaded emulsion-based hydrogel for orthopedic device-related infection
Page P18: D Rajkumar, PPS Balraadjsing, SAJ Zaat
Novel bioactive glass S53P4 cream to prevent orthopedic implant-associated infection
Page P19: I Redenski, S Daoud, A Zigron, R Fadoul, S Srouji
3D-printing of matrix-based wound bioarrays: a means for high throughput evaluation of antimicrobial biomaterials
Page P20: N Reinert, L Bessems, J Onsea, M Morgenstern, WJ Metsemakers
Definition of treatment success and failure in fracture-related infections: a scoping review
Page P21: TA Schweizer, Y Achermann, PP Bosshard
Real-time fluorescence imaging of porphyrin-producing bacterial biofilms on orthopaedic material in vitro
Page P22: TA Schweizer, PP Bosshard, Y Achermann
Biosurfactants improve detachment and recovery of bacteria from orthopaedic implants – An in vitro study
Page P23: T Schiemer, C Siverino, FT Moriarty, S Zeiter, K Klavins
Serum metabolite changes in a fracture-related infection model
Page P24: JL van Agtmaal, C Calligaro, SWG van Hoogstraten, L Peeters, L Lieu, A Akkache, NE Vrana, JJC Arts
Antimicrobial spray-coating using poly-epsilon-lysine and hyaluronic acid to prevent prosthetic joint infection
Page P25: JL van Agtmaal, SWG van Hoogstraten, JJC Arts
Prosthetic joint infection research models in NWZ rabbits: opportunities for standardization – a systematic review
Page P26: LS van Hofwegen, M Hassnain, A Pan, PPS Balraadjsing, S Nizamoglu
Carboxylized graphene quantum dots in a novel antimicrobial coating
Page P27: R Youf, R Schewior, G Mannala, Y Zhao, V Alt, M Riool
Galleria mellonella larvae: a promising animal model to study biofilm maturation in orthopaedic infections
Page P28: F Weisemann, C Siverino, P Fehrenbach, K Trenkwalder, A Heider, G Atkins, TF Moriarty, S Hackl
Diagnosis of infected and aseptic non-union correlating local gene expression and systemic proteomics, miRNA, and immune cells profiles
age P29: SAJ Zaat, R Li, L van Hofwegen, N Vavilthota, L de Boer, JA Loontjens, M Riool
A novel quaternary ammonium coating of titanium implants prevents murine staphylococcal biomaterial-associated infection
Page P30: S Zhang, Y Elbs-Glatz, S Tao, Z Li, M Rottmar, K Maniura, Q Ren
Probiotic therapy promotes wound healing by modulating PI3K- and TGF-Smad signaling pathways
Page P31: Y Zhao, GK Mannala, R Youf, R Schewior, M Rupp, V Alt, M Riool
Evaluation of antibiotic-loaded bone cement and cemented k-wires against bacterial infections in galleria mellonella
Page P32: L Zhuoang, T Jiajun, C Qiuhong, W Liang
Characteristics, diagnosis, and treatment experience of brucella spondylitis in non-endemic areas: a retrospective study in guangdong province, China