eCM Meeting Abstracts 2014, Collection 6
Abstracts of the Tissue and Cell Engineering Society (TCES)
meeting
on 2-4 July 2014 at Newcastle University.
All abstracts: click here to download all the abstracts in one file
ORAL PRESENTATIONS
Page 1: F Henson
The use of large animal models in the pipeline from bench to clinic
Page 2: AA Janeczek, RS Tare, E Scarpa, TA Newman, ROC Oreffo, ND Evans
Influencing the skeletal stem cell niche by targeted liposomal wnt delivery
Page 3: LE McNamara, JN Roberts, J Sahoo, KV Burgess, J Hay, H Anderson, ROC Oreffo, R Ulijn, MJ Dalby
Page 4: YM Baba Ismail, O Bretcanu, KW Dalgarno, AJ El Haj
Synthesis and in vitro biocompatibility of multi-substituted hydroxyapatite for bone tissue engineering applications
Page 5: J Dugan. F Claeyssens
Photochemical functionalisation and direct-write patterning of diamond-like-carbon for neural interfaces
Page 6: D Thomas, N Tan, R Brown
Real time spatial monitoring system for 3d culture models
Page 7: H Kose, AJ Deegan, S Yucel, Y Yang
Investigation of potential osteogenesis influence of carbon based nanomaterials
Page 8: LJ White, O Qutachi, EL Smith, D Gothard, J Kanczler, ROC Oreffo, KM Shakesheff
Hydrogels from demineralized and decellularized bone extracellular matrix for bone regeneration
Page 9: J Dawson, D Gibbs, C Black, E Scarpa, S Meakins, R Oreffo
Clay gels localise and enhance BMP2 induction of osteogenesis
Page 10: C O’Rourke, R Drake, J Loughlin, JB Phillips
Adapting aligned, stabilised 3d tissues for large-scale neurobiological research
Page 11: P Sawadkar, P Sibbons, L Bozec, V Mudera
Engineering of a functional tendon using load bearing suture technique and tissue engineered collagen graft: an in vivo study
Page 12: AR Armiento, F Dell’Accio, C De Bari
Identification of distinct niches of functional mesenchymal stem cells in bone marrow and synovial tissues in a mouse model of joint surface injury
Page 13: GD Pemberton, P Childs, S Reid, N Gadegaard, R Burchmore, ASG Curtis, M Dalby
Nano-kicking stem cells into making bone
Page 14: MC de Andrés, K Imagawa, A Takahashi, ROC Oreffo
Hypermethylation in OA - Transactivation of the COL9A1 proximal promoter region by SOX9 in chondrocytes is regulated by DNA methylation
Page 15: C-M Horejs, A Serio, A Purvis, AJ Gormley, S Bertazzo, A Poliniewicz, AJ Wang, P DiMaggio, E Hohenester, MM Stevens
The “cryptic” extracellular matrix and its impact on stem cell differentiation
Page 16: C Knight, P Genever
EGF and PDGF elicit Wnt-independent β-catenin signalling in mesenchymal stromal cells via integrin-linked kinase
Page 17: J Marshall, X Yang, P Genever
Mesenchymal stromal cells organise endothelial networks through pdgf, ilk and fgf signaling
Page 18: L Zilic, JW Haycock, S-P Wilshaw
Development of an acellular xenogeneic nerve graft
Page 19: J Wong, R Brown
Control of collagen hydrogel compression for cell rescue
Page 20: D Gothard, JM Kanczler, JA Wells, ROC Oreffo
Characterisation of distinct regional and immuno-selected cell populations derived from human foetal femurs and their capacity for bone defect repair and regeneration
Page 21: A Rodrigo-Navarro, P Rico, A Saadeddin, M Salmeron-Sanchez
Living biointerfaces to direct cell function
Page 22: A Chhatwal, S Przyborski
The effect of long-term 3D culture on cell morphology and behavior
Page 23: L Sidney, S Dunphy, L White, F Rose, A Hopkinson
Engineering the corneal stroma: the effect of a three-dimensional environment and growth factor supplementation
Page 24: ES McMorrow, J Pertek, E Kingham, S Mahajan, M Dalby, N Gadegaard, ROC Oreffo
Modulation of human skeletal stem cell fate and function as a consequence of nanotopography and hypoxia
Page 25: CA Smith, P Rooney, T Board, SM Richardson, JA Hoyland
Cell and bone donor age influence the osteogenic activity of mscs cultured on an osteoinductive washed human bone scaffold
Page 26: A Glen, D Curtis, A Holder, J Morris, C Wright, R Williams, K Hawkins, P Stephens
Development of a novel biorheometer¬¬ for in vitro real time monitoring of matrix remodeling
Page 27: S Partridge, K Dalgarno, A McCaskie, M Birch
Enhanced osteogenesis of hmsc in hydroxyapatite/fibrin gels
Page 28: M Benning
Electrostatic stabilisation of bio-ink through the cationic encapsulation of cells for piezo drop on demand inkjet printing
Posters
Page 29: L Sidney, M Branch, O McIntosh, H Dua, A Hopkinson
Corneal stromal cells: a potential cell source for ocular surface regeneration
Page 30: B Shaharuddin, C Osei-Bempong, S Ahmad, P Rooney, S Ali,
R Oldershaw, A Meeson
Limbal mesenchymal stem cells; alternative stem cells for transplantation
Page 31: SL Wilson, LE Sidney, SE Dunphy, HS Dua, A Hopkinson
Supplementing the corneal donor pool using human decellularised corneas
Page 32: B Shaharuddin, C Osei-Bempong, S Ahmad, P Rooney, S Ali,
R Oldershaw, A Meeson
Limbal mesenchymal stem cells; alternative stem cells for transplantation
Page 33: E Scarpa, JL Bailey, AA Janeczek, ROC Oreffo, TA Newman, ND Evans
The use of polymersomes in stem-cell specific targeting for bone regeneration
Page 34: G Gigliobianco, S Roman, CK Chong, S MacNeil
Surface functionalization of electro-spun poly(L)Lactic acid scaffolds with heparin to induce angiogenesis
Page 35: N Alharbi, K Dalgarno, O Bretcanu
Indirect three dimensional printing (3dp)of apatite-wollastonite (a-w) scaffolds
Page 36: P Ramakrishnan, M Maclean, S MacGregor, J Anderson, MH Grant
Optimising 405 nm hins-light technology for patient safe decontamination during arthroplasty surgery
Page 37: S Müller, L Nicholson, JR De Havilland, A Dickinson, X Nong-Wang
Population kinetics of MSCs in the development of bio-artificial bone scaffolds
Page 38: S Toumpaniari, M Birch, A McCaskie, K Dalgarno
Effect of nano- and microscale roughness on cellular behavior
Page 39: PM Tsimbouri, RK Silverwood, P Fairhurst, T Sjostrom, B Su, P Young, RDM Meek, MJ Dalby
Analysis of osteoclastogenesis/osteoblastogenesis using human bone marrow derived co-cultures on nanotopographical titania surfaces
Page 40: MM Pardo-Figuerez, DJ Player, NRW Martin, SDR Christie, MP Lewis
Towards the smart prosthesis: joining materials and biology
Page 41: NM Wragg, DJ Player, Y Liu, MP Lewis
Preclinical musculoskeletal junction testbed: optimisation of a reproducible skeletal muscle construct
Page 42: EEL Lewis, MJ Dalby, CC Berry
Development of mesenchymal stem cell niche in vitro using magnetic nanoparticles
Page 43: M McCully, J Conde, PV Baptista, MJ Dalby, CC Berry
Increasing osterix expression by blocking mir-31 with rna conjugated gold nanoparticles
Page 44: KE Wright, TI Maisey, SL Perry, DG Jayne
In vitro modelling of human gastrointestinal peritoneal carcinomatosis: a pre-clinical photodiagnostic & photodynamic therapy treatment tool
Page 45: CHC Sims, E Knight, SA Przyborski
The effect of physical microenvironment on the shape of pluripotent stem cells and their developmental potential
Page 46: J Clarke, JW Haycock, F Claeyssens
Fabrication & functionalisation of nerve guidance conduits
Page 47: G Tetteh, IU Rehman, GC Reilly
Bioactive scaffolds as bone templates for in-vitro testing
Page 48: T Eriksson, S Fedele, R Day, V Salih
Development of a three-dimensional model for ameloblastoma
Page 49: KE Clarke, A Whiting, SA Przyborski
Optimisation of a novel neurite outgrowth model to study the role of neurite inhibition in human stem cell derived neurons
Page 50: H Suhaimi, S Wang, DB Das
Nutrient transport properties of tissue engineering membranes and scaffolds
Page 51: DJ Player, NRW Martin, MP Lewis
Development of pre-clinical musculoskeletal models to investigate the onset and degeneration of osteo-arthritis
Page 52: NDP Robinson, D Hill, P Lovat, SA Przyborski
Development of novel 3D skin models to study barrier function
Page 53: MC de Andrés, A Takahashi, K Alvarez, ROC Oreffo
Demethylation of a crucial nf-κb enhancer element orchestrates inos induction in osteoarthritis
Page 54: SB Walsh, KW Dalgarno, AW McCaskie, MA Birch
Novel polymer topography to influence mesenchymal stem cell behavior
Page 55: MC de Andrés, A Takahashi, K Alvarez, ROC Oreffo
Demethylation of a crucial nf-κb enhancer element orchestrates inos induction in osteoarthritis
Page 56: A Baki, O Qutachi, T Gould, E Overton, K Shakesheff, C Rahman
Surface modification of injectable microspheres for cell therapy applications
Page 57: A Aladdad, LJ White, C Alexander, FRAJ Rose
Dynamic patterned electrospun fibres for 3d cell growth
Page 58: EL Smith, CA Roberts, ROC Oreffo
Directional cues for bone regeneration in the avian growth plate
Page 59: X Weng-Jiang, V Salih, RA Brown
Do chondrogenic atdc5 cells in dense collagen make a simple cartilage?
Page 60: A Alraies, E Canetta, R Waddington, R Moseley, A Sloan
Discrimination between high and low proliferative/regenerative dental pulp progenitor cell clones for tissue engineering by raman spectroscopy
Page 61: IO Asencio, S MacNeil, A Crawford, P Hatton, F Claeyssens
Introducing complexity in biomedical devices throughout the incorporation of artificial stem cell microenvironments
Page 62: KA Luetchford, JB Chaudhuri, PA De Bank
Silk-based microparticles as an osteogenic scaffold for tissue engineering
Page 63: JE Dixon, G Morris, N Lane, C Denning, KM Shakesheff
Get: glycosaminoglycan (gag)-binding enhanced transduction of functional proteins
Page 64: J Chen, S Wilson
Nanoindentation of hydrogel composites determined by a flat punch tip
Page 65: J Chen, P Duan
Nanomechanical responses of biopolymer composites determined by nanoindentation with a conical tip
Page 66: J Chen, J Hood
Nanomechanics of bioimplant infection related bacteria
Page 67: SB Walsh, KW Dalgarno, AW McCaskie, MA Birch
Novel polymer topography to influence mesenchymal stem cell behavior
Page 68: L Lawlor, R Grigg, X Yang
A novel hdaci can improve osteogenic differentiation of human adipose derived stem cells
Page 69: K Bardsley, I Wimpenny, H Bin, Y Yang, JA El Haj
Non-destructive in vitro tools for the comparison of degradable biomaterials
Page 70: AA Popov, G Roberts, DM Grant, CA Scotchford, V Sottile
Porous chitosan constructs support bone marrow stem cells for osteochondral modelling
Page 71: RL Pallan, JL Tipper, J Fisher, S Williams
Biological characterisation of the porcine acetabular labrum
Page 72: MR Mohamad, P Riches, MH Grant
The effects of decellularisation on the mechanical properties of bone
Page 73: Y Reinwald, KHL Leonard, JR Henstock, P Levesque, AJ El Haj
Hydrostatic force bioreactor-a novel tool for mechanical conditioning of cells, tissues and tissue constructs
Page 74: V Moulisová, M Cantini, M Salmeron-Sanchez
Promoting vascularisation in bioactive microenvironments
Page 75: G Morris, J Bridge, A Knox, J Aylott, O Eltboli, C Brightling, A Ghaemmaghami, F Rose
Human airway smooth muscle maintain in situ cell orientation and phenotype when cultured on aligned electrospun scaffolds
Page 76: R Chandaria, LJ White, M Ilyas, FRAJ Rose
In vitro culture of colonic epithelial stem cells
Page 77: PE Agbekoh, C Henderson, PE Riches, MH Grant
Effect of cultured rat primary hepatocytes on the mechanical properties of collagen gel matrices
Page 78: E Mancuso, MA Birch, M Marshall, KW Dalgarno, OA Bretcanu
Preliminary evaluation of novel bioceramics for bone restoration
Page 79: A Raza, H Colley, E Baggaley, S Botchway, S MacNeil, JA Weinstein, JW Haycock
Oxygen difference in live melanoma muticellular tumour spheroids using novel platinum compound and time-resolved imaging microscopy
Page 80: S Acott, R Acione, M Ellis
Analysis of positional and rotational variables for cell seeding on hollow fibres
Page 81: CJ Pateman, AJ Harding, R Plenderleith, S Rimmer, FM Boissonade, F Claeyssens, JW Haycock
3d micro-printing of nerve guides for peripheral nerve repair
Page 82: J Patient, K Harris, B Arbahamsson, C Tannergren, A Ghaemaghammi, LJ White, P Williams, C Roberts, FRAJ Rose
Assessing the barrier performance of an in vitro co-culture model of the intestine
Page 83: I Moreno, JM Kanczler, NR Evans, ROC Oreffo
The chorioallantoic membrane (cam) as a capillary bed for human bone angiogenic analysis: the potential of laponite clay gel for growth factor delivery ex vivo
Page 84: HM. Eltaher, J Yang, JE, Dixon, KM Shakesheff
Intracellular transduction of proteins in three dimensional gradients
Page 85: MC Turner, DJ Player, NRW Martin, MP Lewis
Tissue engineering skeletal muscle to investigate glucose uptake
Page 86: D Gothard, EL Smith, JM Kanczler, JA Wells, CA Roberts, LJ White, O Quatachi, MS Sawkins, H Peto, H Rashidi, J Henstock, M Rotherham, L Rojo, MM Stevens, A El Haj, FRAJ Rose, KM Shakesheff, ROC Oreffo
Tissue engineered bone through the use of novel alginate/bone ecm hydrogels
Page 87: H Stobbs, D Player, A Sharples, M Lewis
Ameliorating the effects of tissue engineered skeletal muscle atrophy with mechanical overload: relevance to osteoarthritis?
Page 88: ER Britchford, KM Shakesheff, LDK Buttery, S Allen, GR Kirkham
Cell micro-patterning on polyhema using 1,1’-carbonyldiimidazole as a surface modification intermediate
Page 89: R Howard-Jones, M Wiltshire, A Sloan, R Errington
Heterogeneity of dental pulp progenitor cells
Page 90: L Szkolar, AF Miller, JE Gough, A Saiani
Modification of peptide self-assembling hydrogels for cell culture applications
Page 91: C Liu, S Partridge, K Dalgarno
In situ synthesis of Biomimetic collagen and hydroxyapatite composite
Page 92: L Dew, CK Chong, S MacNeil
Towards the prevascularisation of tissue-engineered skin
Page 93: J Lemmens, S MacNeil, S Przyborski, JW Haycock
Development of 3d skin models for in vitro testing
Page 94: O Qutachi, J Vetsch, D Gill, H Cox, S Hofmann, R Müller, R Quirk, K Shakesheff, C Rahman
Porous biodegradable microspheres that form highly porous scaffolds after injection
Page 95: GR Kirkham, E Britchford, T Upton, J Ware, LD Buttery, S Allen, G Gibson, M Padgett, K Shakesheff
Holographic optical tweezers as a tool for the study of stem cell microenvironments
Page 96: J Price, JR Henstock, AJ El Haj
Cyclic hydrostatic pressure enhances bone growth and repair in an ex vivo non-union defect model
Page 97: KE Wright, TI Maisey, DG Jayne
In vitro detection of ppix fluorescence in human colon cancer cells- towards better pre-surgical photodiagnosis and staging of bowel cancers
Page 98: N Alom, H Peto, KM Shakesheff
Production of growth factors for use in regenerative medicine application
Page 99: S Wilkinson, K Dalgarno, M Birch, E Martin
Serum-free medium development for the expansion of bone marrow derived-mesenchymal stem cells
Page 100: H Markides, D Sagar, O Kehoe, RH Morris, V Chapman, AJ El Haj
Correlating mesenchymal stem cell delivery with pain in an oa rat model
Page 101: H Al-Kharobi, R El-Gendy, D Devine, J Beattie
The role of insulin-like growth factor (igf) binding proteins in osteogenic differentiation of human dental pulp stromal cells derived from healthy and carious teeth
Page 102: MK Kolar, CJ Pateman, LN Novikov, M Wiberg, F Claeyssens, JW Haycock, PJ Kingham
Comparison of 3d micro-printed polycaprolactone conduits and fibrin conduits for peripheral nerve repair
Page 103: S Upson, D Fulton, M German, K Dalgarno
In vitro degradation of novel resorbable polymers for maxillofacial applications
Page 104: R Webb, T Heathman, CL Dong, X Sun, Z Zhang,N Forsyth, A El Haj
Controlled production of poly(3-hydroxybutyrate- co-3-hydroxyhexanoate) (PHBHHx) nanoparticles for use in tissue engineering
Page 105: SS Chowdhury, A Baki, O Qutachi, FRAJ Rose, KM Shakesheff, CV Rahman
Cross-flow membrane emulsification for tunable-sized monodisperse microparticles
Page 106: LA Castillo, JE Gough, A Saiani, AF Miller
Human osteoblasts within soft peptide hydrogels promote mineralisation in vitro
Page 107: J Bratt, S Dunphy, N Forsyth, A El Haj
Mechanical and viscoelastic properties of collagen-elastin hydrogels for lung tissue engineering
Page 108: T Magdeldin, M Loizidou, U Cheema
Tissue engineering a physiologically and spatially relevant 3D in vitro model of colorectal cancer
Page 109: LCY Lee, N Gadegaard, S Yarwood, ROC Oreffo, RMD Meek, MJ Dalby
Investigating self-renewal of mesenchymal stem cells on nanotopography
Page 110: LA Bosworth, AK Ghag, F Tancred-Holmes, SH Cartmell
The effects of polymer grade and sterilisation on electrospun fibre material properties and cell response
Page 111: P Mistry, A Canning, K Shakesheff, J Yang
Bioprinting of vascularised liver tissues
Page 112: DST Chong, N Gadegaard, G Hamilton, AM Seifalian, MJ Dalby
Topographical modification of nanocomposite polymer vascular graft surfaces to optimise endothelialisation
Page 113: S Shahana, A Roelofs, C De Bari
A comparative genome wide transcriptional analysis of human bone marrow, synovial and periosteal mesenchymal stem cells
Page 114: SJ Avery, AJ Sloan, RJ Waddington
Elucidating novel roles for dentine matrix components in directing stem cell biology
Page 115: J Munguía, K Dalgarno
Arthroscopic delivery of bio-active materials: a preliminary study
Page 116: OR Evans, JB Phillips, RJ Shipley
A mathematical framework for nerve regeneration in implantable conduits
Page 117: A Lisella, AJ El Haj
Determination of drug permeability in caco-2 monolayers under dynamic conditions using a novel magnetic force bioreactor technology
Page 118: HTJ Gilbert, SM Richardson, JA Hoyland
Development of a stem cell therapy for repair of the degenerate IVD: Influence of pH on nucleus pulposus and mesenchymal stem cells
Page 119: JC Bridge, GE Morris, J Aylott, MP Lewis, FRAJ Rose
Developing an in vitro model to measure airway smooth muscle contraction
Page 120: N Wung, ZD Burke, MJ Ellis, D Tosh
Novel hepatocyte-like cells and biomaterial for bioartificial liver design
Page 121: N Rodrigues, N Alharbi, M Benning, J Mungia, K Dalgarno
Materials processing for the manufacture of musculoskeletal medical devices at the point of need
Page 122: JR Henstock, M Rotherham, AJ El Haj
Remotely controlled mechanotransduction via magnetic nanoparticles: applications for injectable cell therapies
Page 123: A Khadre, R El-Gendy, O-M Goudouri, W Refaat, A Ramadan, A Boccaccini, E Raif
Scaffolds’ characterisation for a multilayered construct simulating the tooth periodntium
Page 124: C Sherborne, DW Johnson, MP Didsbury, C Pateman, N Cameron, F Claeyssens
3d printing of high internal phase emulsions for cell culture applications
Page 125: R Balint, SH Cartmell
Low density culturing maintains HMSCs in their highly proliferative state and improves their osteogenic differentiation potential
All abstracts: click here to download all the abstracts in one file